Effect of the angiotensin II type 2-receptor gene (+1675 G/A) on left ventricular structure in humans.

@article{Schmieder2001EffectOT,
  title={Effect of the angiotensin II type 2-receptor gene (+1675 G/A) on left ventricular structure in humans.},
  author={Roland E Schmieder and Jeanette Erdmann and Christian Delles and Johannes Jacobi and Eckart Fleck and Karl Friedrich Hilgers and Vera Regitz-Zagrosek},
  journal={Journal of the American College of Cardiology},
  year={2001},
  volume={37 1},
  pages={175-82}
}
OBJECTIVES Our study goal was to analyze whether gene variants of angiotensin II type 2-receptor (AT2-R) modulate the effects of angiotensin II on the left ventricle (LV). BACKGROUND Experimental data suggest that angiotensin II modifies ventricular growth responses via angiotensin II type 1-receptors (AT1-R) and AT2-R. METHODS In 120 white, young male subjects with normal or mildly elevated blood pressure, we assessed plasma angiotensin II and aldosterone concentrations (RIA), 24-h urinary… CONTINUE READING