Effect of the O-antigen length of lipopolysaccharide on the functions of Type III secretion systems in Salmonella enterica.

@article{Hlzer2009EffectOT,
  title={Effect of the O-antigen length of lipopolysaccharide on the functions of Type III secretion systems in Salmonella enterica.},
  author={Stefanie U. H{\"o}lzer and Markus C. Schlumberger and Daniela J{\"a}ckel and Michael Hensel},
  journal={Infection and immunity},
  year={2009},
  volume={77 12},
  pages={5458-70}
}
The virulence of Salmonella enterica critically depends on the functions of two type III secretion systems (T3SS), with the Salmonella pathogenicity island 1 (SPI1)-encoded T3SS required for host cell invasion and the SPI2-T3SS enabling Salmonella to proliferate within host cells. A further T3SS is required for the assembly of the flagella. Most serovars of Salmonella also possess a lipopolysaccharide with a complex O-antigen (OAg) structure. The number of OAg units attached to the core… CONTINUE READING

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