Effect of the HIV-1 syncytium-inducing phenotype on disease stage in vertically-infected children.

@article{Fitzgibbon1998EffectOT,
  title={Effect of the HIV-1 syncytium-inducing phenotype on disease stage in vertically-infected children.},
  author={Joseph E. Fitzgibbon and Sunanda Gaur and M{\'a}rta G{\'a}vai and Patrice B Gregory and Lawrence Dean Frenkel and Joseph F John},
  journal={Journal of medical virology},
  year={1998},
  volume={55 1},
  pages={56-63}
}
The syncytium-inducing (SI) capability of HIV-1 isolates from 48 HIV-infected children was determined in order to examine the association of the SI phenotype with an AIDS diagnosis and/or with other clinical parameters in HIV-infected children. In a retrospective cross-sectional analysis, phenotypic data were linked to clinical and immunologic data from each patient. Multiple longitudinal samples were analyzed from 14 patients. Children with SI viruses were older than children with nonsyncytium… CONTINUE READING

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