Effect of the Antiviral Drug, Cytosine Arabinoside, on the Developing Nervous System

@article{Ashwal1974EffectOT,
  title={Effect of the Antiviral Drug, Cytosine Arabinoside, on the Developing Nervous System},
  author={Stephen Ashwal and Milton L Finegold and Irving Fish and Gleb N. Budzilovich and Philip Alfred Brunell},
  journal={Pediatric Research},
  year={1974},
  volume={8},
  pages={945-950}
}
Extract: Cytosine arabinoside (which is used to treat congenital viral infections) produced neurologic and retinal damage in infant mice. Station and gait abnormalities could be related to hypoplasia and marked microscopic changes in the cerebellum of treated animals. These, as well as microscopic changes in the retina, appeared to be irreversible. The… CONTINUE READING