Effect of the 13-valent pneumococcal conjugate vaccine on invasive pneumococcal disease in England and Wales 4 years after its introduction: an observational cohort study.

@article{Waight2015EffectOT,
  title={Effect of the 13-valent pneumococcal conjugate vaccine on invasive pneumococcal disease in England and Wales 4 years after its introduction: an observational cohort study.},
  author={Pauline A. Waight and Nicholas John Abbott Andrews and Shamez N Ladhani and Carmen L Sheppard and Mary P. E. Slack and Elizabeth L. Miller},
  journal={The Lancet. Infectious diseases},
  year={2015},
  volume={15 5},
  pages={
          535-43
        }
}
BACKGROUND The 13-valent pneumococcal conjugate vaccine (PCV13) protects against key serotypes that increased after routine immunisation with the seven-valent vaccine (PCV7), but its potential for herd protection and serotype replacement is uncertain. The aim of this study was to analyse the effect of the 13-valent pneumococcal conjugate vaccine on invasive pneumococcal disease in England and Wales 4 years after its introduction. METHODS We used a national dataset of electronically reported… CONTINUE READING
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