Effect of tetramethylpyrazine on lipid peroxidation in streptozotocin-induced diabetic mice.

Abstract

Oxygen free radicals have been suggested to be a contributory factor in complications of diabetes mellitus. In the present study, we investigated the effect of tetramethylpyrazine (TMP) (10, 25 and 50 mg/kg), an active component of a Chinese medicinal plant Ligusticum wallich Franch (chuanxiang), on streptozotocin (STZ)-induced diabetic male ICR mice. STZ… (More)

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