Effect of testosterone replacement therapy on prostate tissue in men with late-onset hypogonadism: a randomized controlled trial.

@article{Marks2006EffectOT,
  title={Effect of testosterone replacement therapy on prostate tissue in men with late-onset hypogonadism: a randomized controlled trial.},
  author={Leonard S. Marks and Norman A. Mazer and Elahe Mostaghel and David L. Hess and Frederick J. Dorey and Jonathan I. Epstein and Robert Veltri and Danil V. Makarov and Alan W. Partin and David G. Bostwick and Maria Luz Macairan and Peter S. Nelson},
  journal={JAMA},
  year={2006},
  volume={296 19},
  pages={
          2351-61
        }
}
CONTEXT Prostate safety is a primary concern when aging men receive testosterone replacement therapy (TRT), but little information is available regarding the effects of TRT on prostate tissue in men. OBJECTIVE To determine the effects of TRT on prostate tissue of aging men with low serum testosterone levels. DESIGN, SETTING, AND PARTICIPANTS Randomized, double-blind, placebo-controlled trial of 44 men, aged 44 to 78 years, with screening serum testosterone levels lower than 300 ng/dL (<10.4… CONTINUE READING

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