Effect of terbutaline on movement of Cl- and Na+ across the trachea of the dog in vitro.

The epithelium of canine trachea maintains a transepithelial potential difference (lumen negative relative to submucosa) by active transport of Cl- toward the lumen and of Na+ away from the lumen. This study examined the effects of terbutaline (a beta-adrenergic agonist) on short-circuit current, potential difference, electrical conductance, and fluxes of… CONTINUE READING