Effect of telmisartan on the expression of cardiac adiponectin and its receptor 1 in type 2 diabetic rats.

@article{Guo2011EffectOT,
  title={Effect of telmisartan on the expression of cardiac adiponectin and its receptor 1 in type 2 diabetic rats.},
  author={Zhixin Guo and Caihong Zheng and Zhihong Qin and Ping Wei},
  journal={The Journal of pharmacy and pharmacology},
  year={2011},
  volume={63 1},
  pages={87-94}
}
OBJECTIVES This study investigated the effect of telmisartan on the expression of cardiac adiponectin and its receptor 1 in type 2 diabetic rats. METHODS Thirty-six male Wistar rats were randomly divided into control (C, n = 10) and diabetic (n = 26) groups. Type 2 diabetes was induced by high-fat and high-sugar diet and intraperitoneal injection of a low dose of streptozotocin (STZ). After induction of diabetes, diabetic rats were again randomly divided into diabetic (D, n = 10) and diabetic… CONTINUE READING

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References

Publications referenced by this paper.
Showing 1-10 of 36 references

Adiponectin and AdipoR1 regulate PGC-1alpha and mitochondria by Ca(2+) and AMPK/SIRT1

  • M Iwabu
  • Nature
  • 2010
2 Excerpts

Negative regulation of adiponectin receptor 1 promoter by insulin via a repressive nuclear inhibitory protein element

  • X Sun
  • FEBS Lett
  • 2008
1 Excerpt

The characterization of high-fat diet and multiple low-dose streptozotocin induced type 2 diabetes rat model

  • M Zhang
  • Exp Diabetes Res
  • 2008
1 Excerpt

Targeted disruption of AdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic actions

  • T Yamauchi
  • Nat Med
  • 2007
2 Excerpts

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