Effect of tea polyphenols on the adhesion of highly metastatic human lung carcinoma cell lines to endothelial cells in vitro.

@article{Zheng2012EffectOT,
  title={Effect of tea polyphenols on the adhesion of highly metastatic human lung carcinoma cell lines to endothelial cells in vitro.},
  author={Feng-Jin Zheng and Lin Shi and Jun Yang and Xiao-hui Deng and Yu-quan Wu and Xi-qing Yan and Ning Huang},
  journal={Asian Pacific journal of cancer prevention : APJCP},
  year={2012},
  volume={13 8},
  pages={3751-5}
}
AIM Tea polyphenols are known to play roles in critical steps of human lung carcinoma cell metastasis. For understanding the mechanisms whereby they inhibit tumor metastasis, the present study was conducted to investigate their effects on the adhesion of highly metastatic lung carcinoma cell lines (PG cells) to endothelial cells (EC cells) and adhesion molecule expression in vitro. METHODS The expression of CD44 or CD54 in the PG cells was detected by flow cytometry and adhesion of PG cells… CONTINUE READING