Effect of synthetic human cholecystokinin-33 on pancreatic blood flow in dogs.

@article{Doi1990EffectOS,
  title={Effect of synthetic human cholecystokinin-33 on pancreatic blood flow in dogs.},
  author={Ryuichiro Doi and Ryo Hosotani and Kazutomo Inoue and Masafumi Kogire and Shoichiro Sumi and Nobutaka Fujii and Hiroki Yajima and Phillip L. Rayford and Takayoshi Tobe},
  journal={Pancreas},
  year={1990},
  volume={5 5},
  pages={615-20}
}
We have examined the effect of synthetic human cholecystokinin (CCK-33 and CCK-8) on pancreatic blood flow and protein output in anesthetized dogs. Human CCK-33 and CCK-8 increased pancreatic blood flow and protein output in a dose-related manner. There were no significant differences in increasing pancreatic blood flow between human CCK-33 and CCK-8, and increases in blood flow were closely related to the increase of the pancreatic enzyme secretion. L-364,718 (20 nmol/kg) caused a potent… CONTINUE READING

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