• DOI:10.1016/S0161-6420(81)35052-0
Corpus ID: 26927571

Effect of synthetic cannabinoids on elevated intraocular pressure.

@article{Tiedeman1981EffectOS,
  title={Effect of synthetic cannabinoids on elevated intraocular pressure.},
  author={J. Tiedeman and M. B. Shields and P. A. Weber and J. Crow and D. Cocchetto and W. A. Harris and J. Howes},
  journal={Ophthalmology},
  year={1981},
  volume={88 3},
  pages={
          270-7
        }
}

J. Tiedeman, M. B. Shields, +4 authors J. Howes

Published 1981

Medicine

Ophthalmology

Two chemical derivatives of delta-1-tetrahydrocannabinol were evaluated in a randomized, double-masked study, administered as a single oral dose to a group of ocular hypertensive patients. One of the compounds (BW146Y) was found to have a significant intraocular pressure lowering effect that was independent of orthostatic blood pressure changes, although such changes did occur in some patients. The other compound (BW29Y) was ineffective in lowering intraocular pressure at the doses tested… CONTINUE READING

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