Effect of synbiotic therapy on the incidence of ventilator associated pneumonia in critically ill patients: a randomised, double-blind, placebo-controlled trial

@article{Knight2008EffectOS,
  title={Effect of synbiotic therapy on the incidence of ventilator associated pneumonia in critically ill patients: a randomised, double-blind, placebo-controlled trial},
  author={David J. W. Knight and Dale C Gardiner and Amanda Banks and Susan E. Snape and Vivienne C. Weston and Stig Bengmark and Keith J. Girling},
  journal={Intensive Care Medicine},
  year={2008},
  volume={35},
  pages={854-861}
}
To investigate the effect of enteral Synbiotic 2000 FORTE® (a mixture of lactic acid bacteria and fibre) on the incidence of ventilator associated pneumonia (VAP) in critically ill patients. Prospective, randomised, double blind, placebo controlled trial. Tertiary referral centre, general Adult Intensive Care Unit (ICU). 259 enterally fed patients requiring mechanical ventilation for 48 h or more were enrolled. All patients were enterally fed as per a standard protocol and randomly assigned to… CONTINUE READING