Effect of superovulation on the expression of tissue inhibitor of metalloproteinase-3 in the murine endometrium.

@article{Ku2003EffectOS,
  title={Effect of superovulation on the expression of tissue inhibitor of metalloproteinase-3 in the murine endometrium.},
  author={Seung Yup Ku and Young Min Choi and Chang Suk Suh and Seok Hyun Kim and Jung Gu Kim and Shin Yong Moon and Jin Yong Lee and Yon Su Kim},
  journal={Gynecologic and obstetric investigation},
  year={2003},
  volume={55 1},
  pages={1-6}
}
Matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) are important in the endometrial remodeling process during embryonic trophoblast invasion. Previous studies, using in situ hybridization, revealed that the predominant proteinase expressed by the implanting mouse embryo is matrix metalloproteinase-9 (MMP-9), and the major tissue inhibitor of metalloproteinases (TIMP) produced in the murine endometrium during this period is TIMP-3. Quantitative, competitive-reverse… CONTINUE READING