Effect of sulindac treatment for attenuated familial adenomatous polyposis with a new germline APC mutation at codon 161: report of a case.

@article{Esaki2002EffectOS,
  title={Effect of sulindac treatment for attenuated familial adenomatous polyposis with a new germline APC mutation at codon 161: report of a case.},
  author={Motohiro Esaki and Takayuki Matsumoto and Mitsuru Mizuno and Yoichiro Kobori and Ryuji Yoshimura and Takashi Yao and Mitsuo Iida},
  journal={Diseases of the colon and rectum},
  year={2002},
  volume={45 10},
  pages={1397-402; discussion 1402-6}
}
INTRODUCTION Patients with familial adenomatous polyposis develop colorectal cancers if left untreated. As indicated in patients with familial adenomatous polyposis, prophylactic colectomy has been recommended even in a milder colonic phenotype referred to as attenuated familial adenomatous polyposis. However, therapeutic strategies in attenuated familial adenomatous polyposis are still controversial. METHODS We report a patient with attenuated familial adenomatous polyposis who has been… CONTINUE READING