Effect of sulforaphane on metallothionein expression and induction of apoptosis in human hepatoma HepG2 cells.

Abstract

The molecular mechanism of sulforaphane on the induction of metallothionein (MT) genes in HepG2 cells and the antiproliferative effects of sulforaphane were investigated in this study. Treatment of the cells with sulforaphane at non-toxicity concentration (0-20 microM) resulted in coordinate increases in the induction of MT-I and MT-II mRNA, followed by… (More)

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@article{Yeh2005EffectOS, title={Effect of sulforaphane on metallothionein expression and induction of apoptosis in human hepatoma HepG2 cells.}, author={Chi-tai Yeh and Gow-Chin Yen}, journal={Carcinogenesis}, year={2005}, volume={26 12}, pages={2138-48} }