Effect of substance P on right colonic pressure: a dose response study in pigs.

@article{Bayat1991EffectOS,
  title={Effect of substance P on right colonic pressure: a dose response study in pigs.},
  author={Maryam Bayat and Gitte W Lam and Jens Mortensen and Steen Lindk{\ae}r Jensen},
  journal={Digestive diseases},
  year={1991},
  volume={9 6},
  pages={432-6}
}
The purpose of the present investigation was to elucidate the influence and mechanism of the action of substance P (SP) upon intraluminal pressure in proximal porcine colon. In 9 pigs, SP was infused intra-arterially in varying doses from 0.5 to 160 ng/kg/min. Mean baseline colonic pressure was 8.9 mm Hg increasing in a dose-dependent manner to 34.6 mm Hg… CONTINUE READING