Effect of subinhibitory concentrations of antibiotics on intrachromosomal homologous recombination in Escherichia coli.

Abstract

Subinhibitory concentrations of some antibiotics, such as fluoroquinolones, have been reported to stimulate mutation and, consequently, bacterial adaptation to different stresses, including antibiotic pressure. In Escherichia coli, this stimulation is mediated by alternative DNA polymerases induced via the SOS response. Sublethal concentrations of the… (More)
DOI: 10.1128/AAC.00358-09

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