Effect of subcutaneous vs intraperitoneal administration of an anti-estrogen, CI-628, estradiol-and estradiol benzoate-stimulated lordosis in the ovariectomized rat.

  • Irène Landau
  • Published 1976 in Pharmacology, biochemistry, and behavior


The anti-estrogen CI-628 (3 mg) inhibited estradiol (E, 150 mug, SC in oil)-stimulated lordosis in ovariectomized rats, when the anti-estrogen was given intraperitoneally (IP) at the time of E injection (Hr 0). No lordosis inhibition occurred after similar treatment, if the CI-628 was given subcutaneously. For estradiol benzoate (EB, 2 mug, SC in oil… (More)