Effect of subconjunctival glucose on retinal ganglion cell survival in experimental retinal ischaemia and contrast sensitivity in human glaucoma.

@article{Shibeeb2016EffectOS,
  title={Effect of subconjunctival glucose on retinal ganglion cell survival in experimental retinal ischaemia and contrast sensitivity in human glaucoma.},
  author={O'Sam Shibeeb and Glyn Chidlow and Guoge Han and John P. M. Wood and Robert J. Casson},
  journal={Clinical & experimental ophthalmology},
  year={2016},
  volume={44 1},
  pages={24-32}
}
PURPOSE This study aims to evaluate the effect of subconjunctival glucose on the retinal ganglion cells (RGCs) in experimental retinal ischaemia and contrast sensitivity in humans with primary open-angle glaucoma (POAG). METHODS First, we measured the intravitreal concentration of glucose at various time points after a subconjunctival injection of 100 μl of 50% glucose to Sprague-Dawley rats. Next, treatment and control groups received 50% subconjunctival glucose and iso-osmotic (8%) saline… CONTINUE READING