Effect of stromal-cell-derived factor 1 on stem-cell homing and tissue regeneration in ischaemic cardiomyopathy

@article{Askari2003EffectOS,
  title={Effect of stromal-cell-derived factor 1 on stem-cell homing and tissue regeneration in ischaemic cardiomyopathy},
  author={Arman T. Askari and Samuel Unzek and Zoran B Popovi{\'c} and Corey K Goldman and Marc S. Penn},
  journal={The Lancet},
  year={2003},
  volume={362},
  pages={697-703}
}
BACKGROUND Myocardial regeneration via stem-cell mobilisation at the time of myocardial infarction is known to occur, although the mechanism for stem-cell homing to infarcted tissue subsequently and whether this approach can be used for treatment of ischaemic cardiomyopathy are unknown. We investigated these issues in a Lewis rat model (ligation of the left anterior descending artery) of ischaemic cardiomyopathy. METHODS We studied the effects of stem-cell mobilisation by use of granulocyte… CONTINUE READING
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