Effect of stevioside on PAH transport by isolated perfused rabbit renal proximal tubule.

@article{Jutabha2000EffectOS,
  title={Effect of stevioside on PAH transport by isolated perfused rabbit renal proximal tubule.},
  author={Promsuk Jutabha and Chaivat Toskulkao and Varanuj Chatsudthipong},
  journal={Canadian journal of physiology and pharmacology},
  year={2000},
  volume={78 9},
  pages={
          737-44
        }
}
Stevioside, a non-caloric sweetening agent, is used as a sugar substitute. An influence of stevioside on renal function has been suggested, but little is known about its effect on tubular function. Therefore, the present study was designed to explore the direct effect of stevioside on transepithelial transport of p-aminohippurate (PAH) in isolated S2 segments of rabbit proximal renal tubules using in vitro microperfusion. Addition of stevioside at a concentration of 0.45 mM to either the… CONTINUE READING
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