Effect of steady-state etravirine on the pharmacokinetics and pharmacodynamics of ethinylestradiol and norethindrone.

@article{SchllerGyre2009EffectOS,
  title={Effect of steady-state etravirine on the pharmacokinetics and pharmacodynamics of ethinylestradiol and norethindrone.},
  author={Monika Sch{\"o}ller-Gy{\"u}re and Thomas N Kakuda and Brian J Woodfall and Fatima Aharchi and Monika Peeters and K. Y. Vandermeulen and Richard M. W. Hoetelmans},
  journal={Contraception},
  year={2009},
  volume={80 1},
  pages={
          44-52
        }
}
BACKGROUND Etravirine, a non-nucleoside reverse transcriptase inhibitor (NNRTI) active against NNRTI-resistant HIV, is an inducer of CYP3A4 and an inhibitor of CYP2C9/19. STUDY DESIGN The effect of etravirine on the pharmacokinetics and pharmacodynamics of ethinylestradiol and norethindrone was assessed in 30 HIV-negative females. Following a run-in cycle with ethinylestradiol/norethindrone, the pharmacokinetics of ethinylestradiol and norethindrone was assessed on Day 15 of Cycle 2… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-10 OF 21 CITATIONS

Similar Papers

Loading similar papers…