Effect of sport stress on lymphocyte transformation and antibody formation.

  title={Effect of sport stress on lymphocyte transformation and antibody formation.},
  author={Jussi Eskola and Olli Ruuskanen and Esa Soppi and Matti K. Viljanen and Mikko J{\"a}rvinen and Harri I Toivonen and Kauko Kouvalainen},
  journal={Clinical and experimental immunology},
  volume={32 2},
The effect of a heavy (marathon, 2.5 hr) and moderate (35 min of running) sport stress on the number and function of lymphocytes, and on the plasma cortisol and leucocyte levels was investigated. Marathon running had a profound effect on the lymphocytes. Though the total number of lymphocytes did not change, their responsiveness to PHA and Con A, especially to PPD, was clearly depressed. The suppression of lymphocyte transformation was transient, the recovery occurring in 24 hr. The marathon… CONTINUE READING

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