Effect of spironolactone on plasma brain natriuretic peptide and left ventricular remodeling in patients with congestive heart failure.

@article{Tsutamoto2001EffectOS,
  title={Effect of spironolactone on plasma brain natriuretic peptide and left ventricular remodeling in patients with congestive heart failure.},
  author={Takayoshi Tsutamoto and Atsuyuki Wada and Kiyoshi Maeda and Naoko Mabuchi and Masaru Hayashi and Takashi Tsutsui and Masato Ohnishi and Masahide Sawaki and Masanori Fujii and Takehiro Matsumoto and Toshiki Matsui and Masahiko Kinoshita},
  journal={Journal of the American College of Cardiology},
  year={2001},
  volume={37 5},
  pages={
          1228-33
        }
}
OBJECTIVES We sought to evaluate the effects of spironolactone on neurohumoral factors and left ventricular remodeling in patients with congestive heart failure (CHF). BACKGROUND Aldosterone (ALD) promotes collagen synthesis and structural remodeling of the heart. Spironolactone, an ALD receptor antagonist, is reported to reduce mortality in patients with CHF, but its influence on left ventricular remodeling has not been clarified. METHODS Thirty-seven patients with mild-to-moderate… CONTINUE READING
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Evolving Role of Natriuretic Peptides from Diagnostic Tool to Therapeutic Modality.

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Is the PARADIGM-HF cohort representative of the real-world heart failure patient population?

  • Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology
  • 2018

ANMCO/ELAS/SIBioC Consensus Document: biomarkers in heart failure

  • European heart journal supplements : journal of the European Society of Cardiology
  • 2017

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References

Publications referenced by this paper.
SHOWING 1-10 OF 31 REFERENCES

[Treatment of heart failure guided by plasma aminoterminal brain natriuretic peptide (N-BNP) concentrations].

  • Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology
  • 2000
VIEW 2 EXCERPTS

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