Effect of spermine on lipid profile and HDL functionality in the streptozotocin-induced diabetic rat model.

@article{Jafarnejad2008EffectOS,
  title={Effect of spermine on lipid profile and HDL functionality in the streptozotocin-induced diabetic rat model.},
  author={Akbar Jafarnejad and S Zahra Bathaie and Manouchehr Nakhjavani and Mohammad Zainie Bin Hassan},
  journal={Life sciences},
  year={2008},
  volume={82 5-6},
  pages={
          301-7
        }
}
This study aimed to investigate the effect of spermine (Spm) as a chemical chaperone and glycation inhibitor on the lipid profile and HDL functionality in the short- and long-term treatment of the STZ-induced diabetic rats. Male Wistar rats were divided into 4 groups (control, n=7; diabetic, n=9). Two groups (named 2 and 3) were injected intraperitoneally with streptozotocin. Control rats (named 1 and 4) were injected with vehicle alone. The treatment of diabetic and control animals (groups 3… CONTINUE READING
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