Effect of some antidepressants on glycaemia and insulin levels of normoglycaemic and alloxan-induced hyperglycaemic mice.

@article{Erenmemiolu1999EffectOS,
  title={Effect of some antidepressants on glycaemia and insulin levels of normoglycaemic and alloxan-induced hyperglycaemic mice.},
  author={Aydin Erenmemişoğlu and Umit Kazim Ozdoğan and Recep Saraymen and Ahmet Tutuş},
  journal={The Journal of pharmacy and pharmacology},
  year={1999},
  volume={51 6},
  pages={741-3}
}
Depression is an important problem among diabetic patients. We have investigated the effect of some antidepressant drugs on plasma glucose and insulin levels in normoglycaemic and alloxan-induced diabetic mice. For this purpose the effects of nortryptiline (as an example of a tricyclic antidepressant) and fluoxetine and sertraline (as examples of selective 5-HT re-uptake inhibitors) were examined on plasma glucose and insulin levels. Nortryptiline significantly increased glucose levels and… CONTINUE READING