Effect of somatostatin and bombesin on secretin-stimulated ductular bile flow in dogs.

@article{Kaminski1983EffectOS,
  title={Effect of somatostatin and bombesin on secretin-stimulated ductular bile flow in dogs.},
  author={Donald L. Kaminski and Yashwant G. Deshpande},
  journal={Gastroenterology},
  year={1983},
  volume={85 6},
  pages={
          1239-47
        }
}
The effects of somatostatin and bombesin on the choleresis produced by intraduodenal acid infusion were evaluated in dogs. Because of the documented effect of these agents on hormone release, serum gastrin and plasma secretin levels were monitored. Intraduodenal acid (12 mmol/h) increased bile flow and bile bicarbonate secretion and nearly doubled systemic plasma secretin levels. Bombesin significantly increased the bicarbonate-rich choleresis produced by intraduodenal acid and increased… Expand
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