Effect of sofalcone on tyrosylprotein sulfotransferase.

  title={Effect of sofalcone on tyrosylprotein sulfotransferase.},
  author={Chinnaswamy Kasinathan and Mohammed T Rizwan and Amalia Slomiany and Bronislaw L. Slomiany},
  journal={General pharmacology},
  volume={25 5},
1. Gastric mucus glycoproteins are actively involved in the maintenance of mucosal integrity and the impairment in their elaboration is often a prominent feature in gastric pathology. In this study, we investigated the effect of an antiulcer drug, sofalcone, on the activity of tyrosylprotein sulfotransferase enzyme involved in the secretion of proteins and glycoproteins in male 8 week old rats. 2. Using poly-Glu6, Ala3, Tyr1 (EAY) as sulfate acceptor, and 3'phosphoadenosine 5'-phosphosulfate… CONTINUE READING