Effect of sodium tauroursodeoxycholate on phalloidin-induced cholestasis in rats.

@article{Ishizaki2001EffectOS,
  title={Effect of sodium tauroursodeoxycholate on phalloidin-induced cholestasis in rats.},
  author={Kaoru Ishizaki and Shigemasa Kinbara and Naoyuki Hirabayashi and Kazuhisa Uchiyama and Masahide Maeda},
  journal={European journal of pharmacology},
  year={2001},
  volume={421 1},
  pages={55-60}
}
We investigated the therapeutic effect of tauroursodeoxycholate on phalloidin-induced cholestasis in rats. Intrahepatic cholestasis was induced by administration of phalloidin (500 microg/kg, i.p.) for 7 days. From the day of the last phalloidin injection, tauroursodeoxycholate (60-360 micromol/kg) was given intravenously twice a day for 4 days. On the next… CONTINUE READING