Effect of small-volume resuscitation on intracranial pressure and related cerebral variables.

@article{Shackford1997EffectOS,
  title={Effect of small-volume resuscitation on intracranial pressure and related cerebral variables.},
  author={Steven R. Shackford},
  journal={The Journal of trauma},
  year={1997},
  volume={42 5 Suppl},
  pages={S48-53}
}
BACKGROUND Head injury outcome is adversely affected by the presence of hypotension. Therapies directed at rapidly correcting hypotension may improve outcome. METHODS In two separate studies, we investigated small-volume resuscitation (4 mL/kg) using Ringer's lactate, hypertonic saline and dextran, and diaspirin cross-linked hemoglobin in a porcine model of cryogenic brain injury and shock. RESULTS Small-volume resuscitation with hypertonic saline and dextran and diaspirin cross-linked… CONTINUE READING

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