Effect of site-specific modification on restriction endonucleases and DNA modification methyltransferases.

@article{McClelland1994EffectOS,
  title={Effect of site-specific modification on restriction endonucleases and DNA modification methyltransferases.},
  author={Michael McClelland and M. Nelson and Eberhard Raschke},
  journal={Nucleic acids research},
  year={1994},
  volume={22 17},
  pages={3640-59}
}
Restriction endonucleases have site-specific interactions with DNA that can often be inhibited by site-specific DNA methylation and other site-specific DNA modifications. However, such inhibition cannot generally be predicted. The empirically acquired data on these effects are tabulated for over 320 restriction endonucleases. In addition, a table of known site-specific DNA modification methyltransferases and their specificities is presented along with EMBL database accession numbers for cloned… CONTINUE READING
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