Effect of sitagliptin on the working memory and reference memory in type 2 diabetic Sprague-Dawley rats: possible role of adiponectin receptors 1.

@article{Sakr2013EffectOS,
  title={Effect of sitagliptin on the working memory and reference memory in type 2 diabetic Sprague-Dawley rats: possible role of adiponectin receptors 1.},
  author={Hussein F. Sakr},
  journal={Journal of physiology and pharmacology : an official journal of the Polish Physiological Society},
  year={2013},
  volume={64 5},
  pages={613-23}
}
  • Hussein F. Sakr
  • Published 2013 in
    Journal of physiology and pharmacology : an…
Type 2 diabetes mellitus (DM) is associated with increased incidence of behavioral changes and memory loss. Memory loss could be caused by Alzheimer's disease (AD) and vascular dementia (VaD). So, we aimed to investigate the effect of sitagliptin in improving the working and reference memories in diabetic rats. Thirty six male Sprague-Dawley rats divided equally (n=12) into three groups: control, type 2 DM and type 2 DM treated with DPP-4 inhibitor (sitagliptin) for one month (10 mg/kg) orally… CONTINUE READING

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