Effect of single-dose anthelmintic treatment during pregnancy on an infant's response to immunisation and on susceptibility to infectious diseases in infancy: a randomised, double-blind, placebo-controlled trial

@inproceedings{Webb2011EffectOS,
  title={Effect of single-dose anthelmintic treatment during pregnancy on an infant's response to immunisation and on susceptibility to infectious diseases in infancy: a randomised, double-blind, placebo-controlled trial},
  author={E L Webb and Patrice Akusa Mawa and Juliet Ndibazza and Dennison Kizito and Alice Namatovu and Jacqueline Kyosiimire-Lugemwa and Bridget Nanteza and Margaret Nampijja and Lawrence Muhangi and Patrick William Woodburn and Hellen Akurut and Harriet Mpairwe and Miriam Akello and Nancy Lyadda and Joseph W Bukusuba and Macklyn Kihembo and Moses Kizza and Robert Kizindo and Juliet Nabulime and Christine Ameke and Proscovia Bazanya Namujju and Robert Tweyongyere and Moses Muwanga and James A G Whitworth and Alison M Elliott},
  booktitle={The Lancet},
  year={2011}
}
BACKGROUND Helminth infections affect the human immune response. We investigated whether prenatal exposure to and treatment of maternal helminth infections affects development of an infant's immune response to immunisations and unrelated infections. METHODS In this randomised, double-blind, placebo-controlled trial, we enrolled 2507 women in the second or third trimester of pregnancy who were planning to deliver in Entebbe General Hospital, Entebbe, Uganda. With a computer-generated random… CONTINUE READING