Effect of single and repeated heat stress on chemical signals of heat shock response cascade in the rat’s heart

Abstract

Exposure to sublethal heat stress activates a complex cascade of signaling events, such as activators (NO), signal molecules (PKCε), and mediators (HSP70 and COX-2), leading to implementation of heat preconditioning, an adaptive mechanism which makes the organism more tolerant to additional stress. We investigated the time frame in which these chemical… (More)
DOI: 10.1007/s12192-017-0863-0

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