Effect of silk protein processing on drug delivery from silk films.

@article{Pritchard2013EffectOS,
  title={Effect of silk protein processing on drug delivery from silk films.},
  author={Eleanor M. Pritchard and Xiao Hu and Violet Finley and Catherine K. Kuo and David L. Kaplan},
  journal={Macromolecular bioscience},
  year={2013},
  volume={13 3},
  pages={
          311-20
        }
}
Sericin removal from the core fibroin protein of silkworm silk is a critical first step in the use of silk for biomaterial-related applications, but degumming can affect silk biomaterial properties, including molecular weight, viscosity, diffusivity and degradation behavior. Increasing the degumming time (10, 30, 60, and 90 min) decreases the average molecular weight of silk protein in solution, silk solution viscosity, and silk film glass-transition temperature, and increases the rate of… CONTINUE READING
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