Effect of sialylated O-glycans in pro-brain natriuretic peptide stability.


BACKGROUND Atrial, brain, and C-type natriuretic peptides (ANP, BNP, and CNP) are important in regulating a variety of cardiovascular and cellular functions. In cells, these peptides are made as proforms that are converted to mature forms. BNP and its related peptides are biomarkers for the diagnosis of heart failure. In this study, we examined… (More)
DOI: 10.1373/clinchem.2009.140558