Effect of sex and assay method on serum concentrations of growth hormone in patients with acromegaly and in healthy controls.

@article{Markkanen2006EffectOS,
  title={Effect of sex and assay method on serum concentrations of growth hormone in patients with acromegaly and in healthy controls.},
  author={Helene M Markkanen and Tuula A Pekkarinen and Matti V{\"a}lim{\"a}ki and Henrik V Alfthan and Ritva Kauppinen-M{\"a}kelin and Timo Sane and U E Stenman},
  journal={Clinical chemistry},
  year={2006},
  volume={52 3},
  pages={468-73}
}
BACKGROUND Diagnosis and follow-up of acromegaly is based on measurements of serum growth hormone (GH) concentrations during an oral glucose tolerance test (OGTT). A nadir value <1 microg/L is commonly used to define a normal response, but some authors suggest lower cutoff values. METHODS To compare the results and subsequent patient classification obtained with 3 GH assays, we obtained basal serum samples from 78 apparently healthy adult controls (43 women and 35 men; median age, 32.5 years… CONTINUE READING

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