Effect of selegiline on mortality in patients with Parkinson's disease: a meta-analysis.

  title={Effect of selegiline on mortality in patients with Parkinson's disease: a meta-analysis.},
  author={Charles W. Olanow and Vilho V. Myllyl{\"a} and Ky{\"o}sti A. Sotaniemi and Jan P. Larsen and Sven E. P{\aa}lhagen and Horst Przuntek and E. H. Heinonen and Olavi Kilkku and Risto Lammintausta and Outi M{\"a}ki-Ikola and Urpo K. Rinne},
  volume={51 3},
INTRODUCTION The Parkinson's Disease Research Group of the United Kingdom (PDRG-UK) reported increased mortality in PD patients treated with levodopa plus selegiline compared with those treated with levodopa alone. METHODS We performed a meta-analysis on five long-term, prospective, randomized trials of selegiline in patients with untreated PD. Included in the analysis were four randomized, double-blind, placebo-controlled studies and one randomized, double-blind, placebo-controlled study of… CONTINUE READING

From This Paper

Topics from this paper.


Publications citing this paper.
Showing 1-10 of 17 extracted citations

Neuroprotection in Parkinson's disease: clinical trials.

Handbook of clinical neurology • 2007
View 4 Excerpts
Highly Influenced

'Bad guys' among the antiparkinsonian drugs.

Psychiatria Danubina • 2009
View 1 Excerpt

[Advances in the medical treatment of Parkinson's disease].

Parkinsonism & related disorders • 2009
View 1 Excerpt

Similar Papers

Loading similar papers…