Effect of selegiline on mortality in patients with Parkinson's disease: a meta-analysis.

@article{Olanow1998EffectOS,
  title={Effect of selegiline on mortality in patients with Parkinson's disease: a meta-analysis.},
  author={Charles W. Olanow and Vilho V. Myllyl{\"a} and Ky{\"o}sti A. Sotaniemi and Jan P. Larsen and Sven E. P{\aa}lhagen and Horst Przuntek and E. H. Heinonen and Olavi Kilkku and Risto Lammintausta and Outi M{\"a}ki-Ikola and Urpo K. Rinne},
  journal={Neurology},
  year={1998},
  volume={51 3},
  pages={825-30}
}
INTRODUCTION The Parkinson's Disease Research Group of the United Kingdom (PDRG-UK) reported increased mortality in PD patients treated with levodopa plus selegiline compared with those treated with levodopa alone. METHODS We performed a meta-analysis on five long-term, prospective, randomized trials of selegiline in patients with untreated PD. Included in the analysis were four randomized, double-blind, placebo-controlled studies and one randomized, double-blind, placebo-controlled study of… CONTINUE READING

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