Effect of selective estrogen receptor modulators on metabolic homeostasis.


Selective estrogen receptor modulators (SERMs) are estrogen receptor (ER) ligands that exhibit either estrogen agonistic or antagonistic activity in a tissue-specific manner. The first and second generation SERMs, tamoxifen and raloxifene, are used for treatment of ER positive breast cancer and postmenopausal osteoporosis respectively. The third-generation… (More)
DOI: 10.1016/j.biochi.2015.06.018


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