Effect of selection on the topology of genealogical trees.

  title={Effect of selection on the topology of genealogical trees.},
  author={Leonardo P. Maia and Alexandre Colato and Jos{\'e} F. Fontanari},
  journal={Journal of theoretical biology},
  volume={226 3},
Selection is one of the factors that most influence the shape of genealogical trees. Here we report results of simulations of the infinite-sites version of Moran's model of population genetics aiming at quantifying how the presence of selection affects the branching pattern (topology) of binary genealogical trees. In particular, we consider a scenario of purifying or negative selection in which all mutations are deleterious and each new mutation reduces the fitness of the individual by the same… CONTINUE READING