Effect of selection of swine for high and low immune responsiveness on monocyte superoxide anion production and class II MHC antigen expression.

@article{Groves1993EffectOS,
  title={Effect of selection of swine for high and low immune responsiveness on monocyte superoxide anion production and class II MHC antigen expression.},
  author={Tim Groves and Bruce N. Wilkie and B. W. Kennedy and Bonnie A. Mallard},
  journal={Veterinary immunology and immunopathology},
  year={1993},
  volume={36 4},
  pages={
          347-58
        }
}
Monocyte function was investigated in second (G2) and third (G3) generation pigs selected for high and low antibody and cell-mediated immune responsiveness. In groups of pigs from the high-and low-immune response lines, monocyte release of superoxide anion (O2-) was assayed in response to phorbol 12-myristate-13-acetate and expression of the Class II-MHC (MHC-II) antigens SLA-DR and SLA-DQ, determined using flow cytometry. Analysis of variance using a linear model demonstrated no significant… CONTINUE READING

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Porcine major histocompatibility complex.

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  • 1998
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