Effect of secretin on bile formation in rats with cirrhosis of the liver: structure-function relationship.

@article{Knuchel1989EffectOS,
  title={Effect of secretin on bile formation in rats with cirrhosis of the liver: structure-function relationship.},
  author={J Knuchel and Stephan Kr{\"a}henb{\"u}hl and Arthur Zimmermann and Juerg Reichen},
  journal={Gastroenterology},
  year={1989},
  volume={97 4},
  pages={950-7}
}
To investigate whether the hypercholeresis seen in cirrhotic humans and animals is due to ductular proliferation or altered inactivation of secretin, or both, we studied the response of bile flow and biliary erythritol clearance to synthetic porcine secretin in rats rendered cirrhotic by chronic exposure to phenobarbital/carbon tetrachloride (n = 11) and… CONTINUE READING