Effect of secretin and VIP on isolated pancreatic duct fragments in vitro.

@article{Creutzfeldt1980EffectOS,
  title={Effect of secretin and VIP on isolated pancreatic duct fragments in vitro.},
  author={W. Creutzfeldt and U. Foelsch},
  journal={Endocrinologia japonica},
  year={1980},
  volume={27 Suppl 1},
  pages={
          59-63
        }
}
A modification of a technique to isolate kidney tubule fragments and pancreatic acinar cells has been used to prepare a suspension of pancreatic duct fragments from rats with pancreatic lipomatosis due to pretreatment with penicillamine and a copper-free diet. This suspension contains almost pure fractions of pancreatic duct fragments. The accumulation of 3',5'-cyclic adenosine monophosphate (cAMP) in response to secretin, VIP and theophylline was studied in these isolated pancreatic duct… Expand
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