Effect of secoverine HCl on motor and myoelectrical activity of the sigmoid colon in man

@article{Meshkinpour1985EffectOS,
  title={Effect of secoverine HCl on motor and myoelectrical activity of the sigmoid colon in man},
  author={H. Meshkinpour and F. Hoehler},
  journal={Drug Development Research},
  year={1985},
  volume={5}
}
Secoverine hydrochloride is a new synthetic tertiary amine with selective muscarine blocking effect. Its tendency to produce parasympathetic side effects has been claimed to be almost 100 times less than atropine. We studied the role of secoverine on meal‐induced colon motor and myoelectrical activity in 12 healthy volunteers. Intraluminal pressure changes, slow wave activity, and spike frequency of the sigmoid colon as well as a pneumogram, blood pressure, and electrocardiogram were monitored… Expand