Effect of screening mammography on breast-cancer mortality in Norway.

@article{Kalager2010EffectOS,
  title={Effect of screening mammography on breast-cancer mortality in Norway.},
  author={Mette Kalager and Marvin Zelen and Fr{\o}ydis Langmark and Hans-Olov Adami},
  journal={The New England journal of medicine},
  year={2010},
  volume={363 13},
  pages={
          1203-10
        }
}
BACKGROUND A challenge in quantifying the effect of screening mammography on breast-cancer mortality is to provide valid comparison groups. The use of historical control subjects does not take into account chronologic trends associated with advances in breast-cancer awareness and treatment. METHODS The Norwegian breast-cancer screening program was started in 1996 and expanded geographically during the subsequent 9 years. Women between the ages of 50 and 69 years were offered screening… 
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TLDR
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TLDR
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Introduction of organised mammography screening was followed by a significant increase in localised and no change in advanced-stage cancers in women eligible for screening relative to younger, ineligible women.
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Despite substantial increases in the number of cases of early-stage breast cancer detected, screening mammography has only marginally reduced the rate at which women present with advanced cancer, suggesting that screening is having, at best, only a small effect on the rate of death from breast cancer.
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TLDR
The seemingly larger effect of screening in Denmark may not be solely attributable to screening itself, but to increased breast cancer mortality in women older than 59 years not invited to screening.
Mortality reductions due to mammography screening: Contemporary population-based data
TLDR
To compare breast cancer mortality in two regions of the Republic of Ireland that introduced a screening programme eight years apart, and to estimate the steady-state mortality deficits the programme will produce, age- and year-matched between-region comparison of breast cancer rates, and of incidence rates of stage 2–4 breast cancer, in the eligible cohorts was carried out.
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