Effect of screening for coronary artery disease using CT angiography on mortality and cardiac events in high-risk patients with diabetes: the FACTOR-64 randomized clinical trial.

@article{Muhlestein2014EffectOS,
  title={Effect of screening for coronary artery disease using CT angiography on mortality and cardiac events in high-risk patients with diabetes: the FACTOR-64 randomized clinical trial.},
  author={Joseph Brent Muhlestein and Donald L. Lapp{\'e} and Joao A. C. Lima and Boaz D. Rosen and Heidi T. May and Stacey Knight and David A. Bluemke and Steven R Towner and Viet T Le and Tami L. Bair and Andrea L. Vavere and Jeffrey L Anderson},
  journal={JAMA},
  year={2014},
  volume={312 21},
  pages={2234-43}
}
IMPORTANCE Coronary artery disease (CAD) is a major cause of cardiovascular morbidity and mortality in patients with diabetes mellitus, yet CAD often is asymptomatic prior to myocardial infarction (MI) and coronary death. OBJECTIVE To assess whether routine screening for CAD by coronary computed tomography angiography (CCTA) in patients with type 1 or type 2 diabetes deemed to be at high cardiac risk followed by CCTA-directed therapy would reduce the risk of death and nonfatal coronary… CONTINUE READING
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