Effect of saturated and unsaturated fatty acids on the oxidative metabolism of human neutrophils. The role of calcium ion in the extracellular medium.

@article{Yamaguchi1986EffectOS,
  title={Effect of saturated and unsaturated fatty acids on the oxidative metabolism of human neutrophils. The role of calcium ion in the extracellular medium.},
  author={Takeo Yamaguchi and Mizuho Kaneda and Katsuko Kakinuma},
  journal={Biochimica et biophysica acta},
  year={1986},
  volume={861 3},
  pages={440-6}
}
The ability of fatty acids to stimulate the generation of superoxide anion (O2-) by human neutrophils was investigated with respect to their Krafft points. Saturated (myristic acid) and unsaturated (elaidic and oleic acid) induced a marked O2- generation and release from human neutrophils at pH 7.4 in the absence of Ca2+, while 0.3 mM Ca2+ inhibited both… CONTINUE READING