Effect of saccharin on antibacterial activity of chlorhexidine gel.

  title={Effect of saccharin on antibacterial activity of chlorhexidine gel.},
  author={Jaime Aparecido Cury and Eduardo Passos Rocha and Hyun Koo and S B Francisco and Altair Antoninha Del Bel Cury},
  journal={Brazilian dental journal},
  volume={11 1},
Although chlorhexidine is the most effective agent against dental plaque it is extremely bitter. To prepare formulations, it is necessary to use flavoring and sweetening, which can inhibit the antibacterial effect of chlorhexidine. Saccharin has been considered a compatible substance to use in chlorhexidine rinse or gel preparations; however, the effect of a range of concentrations has not been studied. To evaluate the effect of different concentrations of saccharin on the antibacterial… CONTINUE READING

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