Corpus ID: 88035478

Effect of rubescensine A on apoptosis and bcl-2,p53,fas/apo-1 and c-myc expression in GBC-SD cells

@article{Shangjun2005EffectOR,
  title={Effect of rubescensine A on apoptosis and bcl-2,p53,fas/apo-1 and c-myc expression in GBC-SD cells},
  author={Yang Shang-jun},
  journal={Journal of Shandong Univenity},
  year={2005}
}
  • Yang Shang-jun
  • Published 2005
  • Biology
  • Journal of Shandong Univenity
  • Objective: To investigate the mechanism of GBC-SD(gallbladder cell-Shandong) apoptosis induced by Rubescensine A. Methods: The presence and pathogenesis of apoptosis were demonstrated by the method of MTT, convert microscopy, electron microscopy, flow cytometry, immunohistochemical assay and spectrofluorometry. Results: After exposure to Rubecensine A , GBC-SD cells were induced to apoptosis in dose-dependent manner, and the level of bcl-2, p53, c-myc and fas/apo-1 were decreased within 24… CONTINUE READING
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